Endocrine Abstracts

Wnt signaling has well-established roles in gonadal development, notably being required for proper sex determination. More recently, a series of descriptive studies has shown the expression of various Wnts and Wnt signaling pathway components in adult ovaries during different stages of follicular development. To determine the potential role of WNT4 in follicle development, a mouse strain bearing a floxed Wnt4 allele was created using standard gene targeting techniques, ...